The winger will get a chance to show what he can do on the international stage, as England prepare for Nations League matches.
The Three Lions take on Hungary, Germany, and Italy in June, and the 25-year-old is likely to play a key role.
Sancho’s teammate Marcus Rashford has also not made the squad after a poor season at Old Trafford.
Full England squad
Defenders:Trent Alexander-Arnold (Liverpool), Conor Coady (Wolves), Marc Guehi (Crystal Palace), Reece James (Chelsea), James Justin (Leicester), Harry Maguire (Man Utd), John Stones (Man City), Fikayo Tomori (AC Milan), Kieran Trippier (Newcastle), Kyle Walker (Man City), Ben White (Arsenal)
Midfielders:Jude Bellingham (Borussia Dortmund), Conor Gallagher (Crystal Palace, on loan from Chelsea), Mason Mount (Chelsea), Kalvin Phillips (Leeds), Declan Rice (West Ham), James Ward-Prowse (Southampton)